Purpose-Built Support for Complex Programs
Neurodegenerative disorders are among the most complex and urgent areas in clinical research. The stakes are high, the timelines long, and the patient populations vulnerable. At inSeption Group, we bring together therapeutic expertise, rare disease experience, and cross-functional continuity to help you navigate these intricacies with clarity and confidence.
Whether you’re developing a therapy for ALS, Parkinson’s, Huntington’s, Alzheimer’s, or a rare or ultra-rare neurologic condition, we support your program from first-in-human through long-term follow-up—with strategic thinking, specialized operations, and a team that’s with you for the full journey.
Built for the long game
Neurodegenerative trials require a different kind of partnership—one built on foresight, flexibility, and deep operational knowledge. That’s where we come in:
Rare disease expertise
We’re experienced in navigating the unique challenges of rare and ultra-rare neurologic conditions: small patient populations, difficult-to-quantify endpoints, gene therapy programs, and caregiver-dependent participation. Our team works closely with specialized sites, advocacy groups, and caregivers to support recruitment, engagement, and retention over the long haul.
Clinical operations and long-term follow-up
Our study teams are trained to manage complex visit schedules, decentralized components, and extended observation periods, ensuring continuity and compliance even as trials span years. We specialize in maintaining patient and site engagement over time, which is critical for data quality and trial integrity.
Neurodegenerative Study Solutions
Soft endpoints: scale strategy and oversight
Soft endpoints—such as clinician- or patient-reported outcome scales—are often central to measuring impact in neurology studies. We bring experience in scale procurement, implementation, and oversight. Our experts review protocols for feasibility and provide strategic guidance on scale selection and use, including evaluating the best-fit modality (e.g., paper, direct EDC entry, or ePRO). Throughout the study, we monitor for inconsistencies or underperformance, enabling timely, targeted training to protect data quality and ensure accurate signal detection.
Medical monitoring and safety support
With neurodegenerative conditions, safety signals can be subtle and require longitudinal context. Our Medical Monitors are adept at detecting trends early, guiding safety decisions, and supporting investigators with nuanced clinical insight.
Biomarkers, imaging, and data strategy
We work across vendors and platforms to ensure alignment between data collection tools and your trial endpoints. From central imaging review to exploratory biomarker management, we bring the systems—and the oversight—to make complex data work for you.
Experienced people. Exceptional partnership.
We don’t rotate people off your program mid-trial or stretch thin resources across multiple studies. Your inSeption team is built with dedicated, senior-level professionals who stay with your study from start to finish. It’s how we deliver continuity, build trust, and help your program run smarter.
Ready to Navigate the Complexities of Neurodegenerative Trials—Together?
When your program demands precision, foresight, and unwavering dedication, inSeption delivers. We’re more than a vendor—we’re an extension of your team, bringing therapeutic insight, operational depth, and the continuity you need to drive progress in even the most complex neurology studies.
“In neurodegenerative research, every detail matters—and so does every person. These trials are long, complex, and emotionally heavy. It’s not just about getting to a data cut. It’s about staying aligned, focused, and human the entire way. That’s what I love about working with inSeption—we stay in it with our clients and our sites, start to finish.”